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When can cytomegalovirus prophylaxis and maintenance therapy be stopped in HIV disease?

Jane R. Deayton1, Paul D. Griffiths

  • 1Department of Virology, Royal Free and University College Medical School, London, UK.

Highly active antiretroviral therapy (HAART) can restore immune responses to a variety of pathogens, including cytomegalovirus. Following successful HAART, prophylaxis and maintenance therapy for cytomegalovirus can safely be stopped in selected patients. However, the risk of cytomegalovirus disease progression recurs if HAART fails, and so these patients require careful monitoring.

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