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Intimate interactions of enteropathogenic Escherichia coli at the host cell surface
R M Delahay1, G Frankel, S Knutton
1Centre for Molecular Microbiology and Infection, Imperial College of Science, Technology and Medicine, London, UK. r.delahay@ic.ac.uk
Current Opinion in Infectious Diseases
|April 20, 2002
Abstract:
Unlike many gastrointestinal pathogens, enteropathogenic Escherichia coli orchestrates the modulation of host cellular and immune responses from the exterior of the infected cell, chiefly via the secreted and translocated components of a type III secretion system. Close inspection of these enteropathogenic Escherichia coli proteins and the interactions they mediate provides an increasingly coherent picture of the pathogenic mechanisms that enteropathogenic Escherichia coli uses to exploit its host.