Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists
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Updated: Oct 1, 2026
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Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
Published on: May 15, 2012
Brad O Buckman1, Ameen Ghannam, Li Angela
1Berlex Biosciences, 15049 San Pablo Ave, Richmond, CA 94804, USA.
Combinatorial Chemistry & High Throughput Screening
|April 23, 2002
Abstract:
An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (K(i) < 100 nM).
