[Epidemiologic and bronchologic aspects of chronic bronchitis in childhood (author's transl)]

Padiatrie Und Padologie
|January 1, 1975
PubMed

Insights

Chronic and relapsing bronchitis in childhood affects 1.64%-3.06% of children. Most cases involve deforming bronchitis, with a good prognosis for many after treatment.

Area of Science:

  • Pediatric Pulmonology
  • Epidemiology
  • Clinical Medicine

Context:

  • Established a definition for chronic and relapsing bronchitis in childhood in the German Democratic Republic (G.D.R.) in 1969.
  • Epidemiological studies in Dresden school children revealed a prevalence rate of 1.64% to 3.06% for this condition.

Purpose:

  • To determine the prevalence, clinical findings, and prognosis of chronic and relapsing bronchitis in childhood.
  • To investigate potential causative factors including malformations, bronchiectasis, bacteriology, immunoglobulin levels, and alpha-1-antitrypsin.

Summary:

  • Bronchologic examinations of 274 children showed deforming bronchitis in 51% and tracheobronchial malformations in 16%. Bronchiectasis was infrequent (9%).
  • Follow-up of 220 children with deforming bronchitis indicated improvement or normalization in 62% after treatment, with deterioration or progression to bronchiectasis in 22%.

Impact:

  • Provides epidemiological data on childhood chronic and relapsing bronchitis in the G.D.R.
  • Highlights deforming bronchitis as a common finding with a generally favorable prognosis following treatment.
  • Identifies key areas for further research into causative factors and management strategies.

Related Concept Videos

Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...