Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Caries risk analysis: considering caries as an individual time-dependent process.

M Kalwitzki1, R Weiger, D Axmann-Krcmar

  • 1Faculty of Dentistry, Department of Conservative Dentistry, University of Tübingen, Tübingen, Germany. matthias.kalwitzki@med.uni-tuebingen.de

International Journal of Paediatric Dentistry
|April 23, 2002
PubMed
Summary

This study estimated the probability of teeth remaining free from cavitated lesions, finding a 5-year probability between 0.89-0.95. Patient caries risk varied significantly, highlighting individual differences in developing end-stage caries.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accuracy of Selective Enamel Etching: A Computer-assisted Imaging Analysis.

Operative dentistry·2023
Same author

European Society of Endodontology position statement: endodontic management of traumatized permanent teeth.

International endodontic journal·2021
Same author

Endodontic management of traumatized permanent teeth: a comprehensive review.

International endodontic journal·2021
Same author

Accuracy of the fluorescence-aided identification technique (FIT) for detecting tooth-colored restorations utilizing different fluorescence-inducing devices: an ex vivo comparative study.

Clinical oral investigations·2021
Same author

Fluorescence-aided Composite Removal in Directly Restored Permanent Posterior Teeth.

Operative dentistry·2019
Same author

Changes in periapical status, quality of root fillings and estimated endodontic treatment need in a similar urban German population 20 years later.

Clinical oral investigations·2018

Area of Science:

  • Dental Public Health
  • Pediatric Dentistry
  • Epidemiology

Background:

  • Dental caries remains a significant public health issue, particularly in pediatric populations.
  • Understanding the progression of caries to the cavitated, or end-stage, lesion is crucial for effective intervention.
  • Patient-specific factors significantly influence caries development and progression rates.

Purpose of the Study:

  • To estimate the probability of a tooth remaining free from a cavitated lesion within defined timeframes.
  • To assess patient-level heterogeneity in the time taken for teeth to develop cavitated lesions.
  • To evaluate the utility of time-to-event analysis in modeling caries progression.

Main Methods:

  • A prospective study design utilizing patient data from a pediatric dentistry clinical course.

Related Experiment Videos

  • Inclusion of 1378 teeth from 41 patients followed for at least 3 years.
  • Application of time-to-event analysis, including a parametric frailty model, to estimate individual caries risk.

    • Main Results:

    • The probability of a tooth remaining free of a cavitated lesion within five years ranged from 0.89 to 0.95 (95% confidence interval).
    • Significant heterogeneity in the true caries risk among patients was observed, exceeding baseline expectations.
    • The frailty model effectively captured individual variations in caries development.

    Conclusions:

    • Time-to-event analysis, particularly with frailty models, provides reliable estimations of caries-free probabilities and individual caries risk.
    • Patient heterogeneity is a critical factor in caries progression that should be accounted for in clinical assessments.
    • This approach enhances the understanding of individual susceptibility to developing end-stage caries.