Related Experiment Videos
BMP signalling: visualisation of the Sog protein gradient
1School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, M13 9PT, Manchester, UK. Hilary.Ashe@man.ac.uk
Current Biology : CB
|April 23, 2002
Abstract:
Extracellular inhibitors are commonly used in development to modulate the activities of signalling molecules. Direct visualisation in the Drosophila embryo of Sog, a Dpp/Scw inhibitor, has now revealed a graded distribution established by degradation and endocytosis.