[Acanthosis nigricans associated with diffuse esophageal papillomatosis]

Two cases of acanthosis nigricans seen in 2 women, the characteristics of which were those of malignant forms, showed oesophageal involvment, the appearance of which was quite similar to that of the mucosal localisations of the syndrome. The authors discuss the features which distinguish the oesophageal localisation of acanthosis nigricans from other types of oesophageal acanthosis or papillomata. In one case, this type of acanthosis, seven years after its onset, was not associated with any detectable malignant change and in the other the cutaneous lesions were improved following surgery at which the associated gastric tumour was not removed.