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Human mitochondrial NADP-dependent isocitrate dehydrogenase in man-mouse somatic cell hybrids
Cytogenetics and Cell Genetics
|January 1, 1976
Abstract:
Human mitochondrial NADP-dependent isocitrate dehydrogenase (IDH-2) is expressed in man-mouse somatic cell hybrids as a dimeric molecule. The gene specifing this enzyme was observed to be syntenic with the mannose phosphate isomerase locus in the 56 primary man-mouse clones in this series. The human IDH-2 locus, therefore, may be assigned to chromosome 15.