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Anterior commissure absence without callosal agenesis: a new brain malformation
T N Mitchell1, J M Stevens, S L Free
1Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, and National Society for Epilepsy, Chalfont-St-Peter, UK.
Neurology
|April 24, 2002
Abstract:
The authors report a novel human brain malformation characterized by the absence of the anterior commissure without callosal agenesis, but associated with gross unilateral panhemispheric malformation incorporating subependymal heterotopia, subcortical heterotopia, and gyral abnormalities including temporal malformation and polymicrogyria. In contrast, a normal anterior commissure was found in 125 control subjects and in 113 other subjects with a range of brain malformations.