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Description of fourteen new DRB alleles found in a stem cell donor registry

T F Tang1, Y-S Lin, F-M Robbins

  • 1Department of Pediatrics, Georgetown University, Washington, DC, USA.

Tissue Antigens
|April 26, 2002
PubMed

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For the same gene multiple alleles can interact to influence phenotypes like the shape and protein composition of an individual cells.By studying allele interactions on the molecular and cellular levels researchers can understand the resulting phenotypes and complications of human conditions like sickle cell trait, improving treatment.The ABO blood group system is a common example of multiple alleles in humans. This system includes three alleles called IA, IB, and i alleles, which combine in...