Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Future trends in bladder reconstructive surgery.

Anthony Atala1

  • 1Laboratory for Tissue Engineering and Cellular Therapeutics, Department of Urology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Seminars in Pediatric Surgery
|April 26, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling.

Drug discovery today·2016
Same author

A tunable hydrogel system for long-term release of cell-secreted cytokines and bioprinted in situ wound cell delivery.

Journal of biomedical materials research. Part B, Applied biomaterials·2016
Same author

Re: A Tumor Mitochondria Vaccine Protects against Experimental Renal Cell Carcinoma.

The Journal of urology·2016
Same author

Re: Endogenous Formaldehyde is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.

The Journal of urology·2016
Same author

Re: Sphaeropsidin A Shows Promising Activity against Drug-Resistant Cancer Cells by Targeting Regulatory Volume Increase.

The Journal of urology·2016
Same author

Re: Sex Hormone-Dependent tRNA Halves Enhance Cell Proliferation in Breast and Prostate Cancers.

The Journal of urology·2016

Avoiding bowel in bladder reconstruction is crucial due to complications. New tissue engineering and expansion techniques show promise for bladder regeneration when traditional methods fail.

Area of Science:

  • Urology
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Incorporating bowel into the urinary tract for bladder reconstruction leads to significant long-term complications.
  • Current methods like auto-augmentation and ureterocystoplasty are limited by patient anatomy (small bladder, unavailable dilated ureters).

Purpose of the Study:

  • To review recent advances in bladder regeneration techniques that avoid enteric epithelium.
  • To explore experimental methods like tissue expansion and tissue engineering for bladder augmentation and regeneration.

Main Methods:

  • Review of current literature on bladder reconstruction techniques.
  • Discussion of experimental approaches including tissue expansion of the ureter and bladder.
  • Examination of tissue engineering strategies for bladder regeneration in animal models.

Related Experiment Videos

Main Results:

  • Tissue engineering for bladder regeneration has shown encouraging results in in vivo animal studies.
  • Experimental techniques involving tissue expansion are being investigated to increase available tissue volume for bladder augmentation.

Conclusions:

  • Novel tissue engineering and tissue expansion methods offer promising alternatives for bladder reconstruction, potentially overcoming limitations of current techniques.
  • These advanced approaches aim to improve outcomes and avoid the complications associated with using bowel segments in the urinary tract.