[Biosensors in the pharmaceutical domain].

Area of Science:

• Analytical Chemistry
• Biotechnology
• Materials Science

Context:

• Biosensors integrate biological recognition elements (enzymes, antibodies, DNA) with physical transducers (electrodes, optical fibers).
• This synergy enables the detection of diverse pharmaceutical compounds through specific biochemical reactions.
• The selection of the biocomponent is application-dependent, optimizing performance criteria.

Purpose:

• To explore the versatile applications of biosensors in pharmaceutical analysis and real-time monitoring.
• To highlight the potential of biosensors in various settings, including bioreactors, home testing, hospitals, and research.
• To discuss the ideal characteristics of biosensors, such as ease of use, automation, and miniaturization.

Summary:

• Biosensors are analytical devices combining biological components with physical transducers for compound analysis.
• They are suitable for real-time monitoring and determining physiological/pharmacological parameters in diverse settings.
• Ideal biosensors are user-friendly, require no sample pre-treatment, and can be automated, miniaturized, or used in arrays.

Impact:

• Biosensors facilitate direct, real-time analysis without complex sample preparation.
• They enable automated, remote-controlled measurements, improving efficiency in clinical and research settings.
• Miniaturized biosensors open possibilities for in vivo monitoring, single-cell analysis, and decentralized testing.