Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pharmaceutical applications of micro-thermal analysis.

Duncan Q M Craig1, V L Kett, C S Andrews

  • 1The School of Pharmacy, The Queen's University of Belfast, 97 Lisburn Road, Belfast, N. Ireland, BT9 7BL, UK. duncan.craig@qub.ac.uk

Journal of Pharmaceutical Sciences
|April 27, 2002
PubMed
Summary

Micro-thermal analysis, a scanning probe microscopy technique, offers localized thermal analysis for polymers and pharmaceuticals. It reveals sample topography and thermal conductivity, aiding in material characterization.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decellularization of porcine small-diameter vascular grafts: evaluation of a latrunculin B-based method and novel perfusion approach.

Biofabrication·2026
Same author

A quality by design study of the use of microfluidic nanoprecipitation for the generation of sub-100 nm drug nanocrystals.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Fabrication and characterization of taste-masked core-shell nanofibre mats for dual drug delivery of antihypertensives in pediatrics.

International journal of pharmaceutics·2026
Same author

Understanding how exposure to drone-induced vibration during transportation affects the quality of a monoclonal antibody (Nivolumab).

International journal of pharmaceutics·2025
Same author

Microfluidic engineering of pDNA nanogels in a coaxial flow reactor: process development, optimisation, scalability and <i>in vitro</i> performance.

Nanoscale advances·2025
Same author

Multistep non-fouling continuous flow synthesis and PEG-functionalisation of biocompatible iron oxide nanoparticles for magnetic hyperthermia, photothermal heating and antifungal activity.

Journal of flow chemistry·2025

Area of Science:

  • Materials Science
  • Analytical Chemistry

Background:

  • Micro-thermal analysis (MTA) integrates scanning probe microscopy with thermal analysis.
  • It utilizes a thermistor-equipped probe for localized thermal measurements.

Purpose of the Study:

  • To outline the principles of micro-thermal analysis.
  • To review its applications in polymer science and pharmaceuticals.

Main Methods:

  • Spatially scanning samples for topography and thermal conductivity.
  • Performing localized thermal analysis on specific sample regions.

Main Results:

  • Demonstrated applications in polymer science.
  • Identified pharmaceutical uses including tablet analysis and characterization of drug-loaded microspheres.

Related Experiment Videos

  • Distinguished amorphous and crystalline regions in semicrystalline samples.

    • Conclusions:

    • Micro-thermal analysis is a versatile technique for localized material characterization.
    • It shows significant potential in pharmaceutical analysis and polymer science.
    • Future directions include further refinement and broader application.