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[Cancer prevention in familial cancer]
1Department of Cancer Epidemiology, Osaka Medical Center for Cancer and Cardiovascular Diseases, 3-3 Nakamichi, 1-Chome, Higashinari-ku, Osaka 537-8511, Japan.
Abstract:
We established a protocol for and will conduct an interventional randomized controlled trial for the prevention of colorectal cancer. The subjects will be 100 patients with hereditary non-polyposis colorectal cancer. Two regimens were formulated for the prevention of colorectal cancer. Regimen A is dietary guidance and ingestion of aged garlic extract (AGE) capsules, and regimen B is dietary guidance and non-function capsules. The main end point of the trial is number and size of colorectal adenomas after 2 years. Subject recruiting was started in March, 2002. The trial will be completed in September, 2005.
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