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[Malignant tumor and hyperfibrinogenemia]
Xiuqiao Liu1, Shujuan Wang, Zhenru Wu
1Department of Clinical Laboratory, Beijing Cancer Hospital, Beijing 100036, China.
Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|April 30, 2002
Abstract
Objective:
To investigate the blood fibrinogen (FIB) content before and after chemotherapy or radiotherapy in 43 malignant tumor patients.
Methods:
COULTER ACL-200 automated coagulation analyzer was used in monitoring FIB in the patients.
Results:
The FIB content was significantly higher in malignant tumor patients than that in benign disease patients. Significant reduction was observed after treatment which became elevated again when there was recurrence or metastasis.
Conclusion:
Assessment of FIB not only helps to diagnose cancers but evaluate the therapeutic effect and prognosis also.