Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alkaloids from Senecio aquaticus.

Veselin S Christov1, Bozhanka P Mikhova, Luba N Evstatieva

  • 1Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria. christov@orgchm.bas.bg

Fitoterapia
|April 30, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Pharmacokinetic characteristics of Bletilla Striata active components in rats and <sup>1</sup>H NMR metabolomics study on ulcerative colitis.

Fitoterapia·2026
Same journal

The cellular and molecular mechanisms of linalool in cancer therapy: Recent advances.

Fitoterapia·2026
Same journal

Phytocomplexes as dual modulators of redox homeostasis and autophagy in host-directed antiviral therapy.

Fitoterapia·2026
Same journal

Contribution of polyphenols in wine grape extract to the inhibition of serine protease activity and proteinase-activated receptor 1-mediated Ca<sup>2+</sup> signaling in vascular endothelial cells.

Fitoterapia·2026
Same journal

Mechanistic insights into a compound essential oil (lemon-Angelica sinensis-Boswellia) for anxiety-melasma comorbidity: An integrated network pharmacology and experimental study.

Fitoterapia·2026
Same journal

Revealing the correlation between chemical composition and pharmacological effects of medicinal plants in the Ilex L. genus.

Fitoterapia·2026
See all related articles

Two pyrrolizidine alkaloids, erucifoline and 9-angeloylhastanecine, were isolated from Senecio aquaticus. Five additional pyrrolizidine alkaloids were identified using gas chromatography-mass spectrometry (GC/MS).

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Pharmacognosy

Background:

  • Pyrrolizidine alkaloids (PAs) are a class of natural compounds found in several plant families.
  • Senecio species are known to produce a diverse range of PAs, some of which possess significant biological activities and toxicities.
  • Understanding the chemical composition of Senecio aquaticus is crucial for assessing its potential medicinal or toxicological properties.

Purpose of the Study:

  • To isolate and identify pyrrolizidine alkaloids from the aerial parts of Senecio aquaticus.
  • To characterize the chemical constituents of this plant species for further research.

Main Methods:

  • Extraction of alkaloids from the aerial parts of Senecio aquaticus.
  • Isolation and purification of compounds using chromatographic techniques.

Related Experiment Videos

  • Identification of isolated and other constituents using Gas Chromatography-Mass Spectrometry (GC/MS) analysis.

    • Main Results:

    • Erucifoline (1) and 9-angeloylhastanecine (2) were successfully isolated and identified.
    • Five additional pyrrolizidine alkaloids, namely jacobine, seneciphylline, spartioidine, jacozine, and senecionine, were tentatively identified by GC/MS.

    Conclusions:

    • The aerial parts of Senecio aquaticus contain a complex mixture of pyrrolizidine alkaloids.
    • The identified alkaloids contribute to the chemotaxonomic understanding of the Senecio genus.
    • Further studies are warranted to investigate the biological activities and toxicological profiles of these isolated and identified PAs.