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Goodpasture syndrome during the course of a Schönlein-Henoch purpura
Luis Carreras1, Rafael Poveda, Jordi Bas
1Department of Nephrology, Hospital Princeps d'Espanya, CUSB, Barcelona, Spain. 4661lcb@comb.es
Abstract:
Two months after surgical resection of a bronchogenic carcinoma, a 69-year-old patient presented with Schönlein-Henoch purpura with kidney involvement followed by pulmonary hemorrhage. The presence of an IgA linear pattern on the kidney biopsy specimen and circulating anti-glomerular basement membrane (GBM) IgA antibodies led to the diagnosis of Goodpasture syndrome, which implies the possibility that the well-known pulmonary involvement during the course of Schönlein-Henoch purpura could be caused by Goodpasture syndrome in certain cases. In cases of glomerulonephropathy with lung involvement, clinicians should not limit their investigations to anti-GBM IgG.
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