Related Experiment Video
Updated: Aug 5, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
[The status of cardiovascular system in electric networks dispatchers]
Insights
Shift work accelerates cardiovascular changes, particularly in blood vessels, by 4-12 years. Dispatcher roles further hasten these effects, highlighting the impact of work patterns on circulatory health.
Area of Science:
- Cardiovascular Physiology
- Occupational Health
Background:
- Aging alters circulatory self-regulation, increasing vascular and decreasing myocardial roles.
- Shift work and specific occupational demands, like dispatching, are linked to cardiovascular changes.
Purpose of the Study:
- To investigate the impact of aging and shift work on cardiovascular regulation and health.
- To determine the influence of shift work duration and dispatcher roles on blood pressure and cardiovascular changes.
Main Methods:
- Analysis of cardiovascular parameters including systolic blood pressure (BP), pulse pressure, and average dynamic BP.
- Correlation of work patterns (shift length, dispatcher duties) with cardiovascular indicators and age of onset for adverse changes.
Main Results:
- Aging shifts circulatory control towards vascular dominance.
- Extended shift work correlates with elevated systolic, pulse, and average dynamic BP.
- Dispatcher roles are associated with a higher systolic BP to pulse rate ratio.
- Shift work accelerates unfavorable cardiovascular changes by 4-12 years, with dispatcher roles adding an additional 2 years.
- Vascular components exhibit the earliest adverse changes.
Conclusions:
- Shift work significantly accelerates the onset of cardiovascular changes, particularly impacting vascular health.
- Occupational factors like shift duration and dispatcher responsibilities play a crucial role in cardiovascular aging.
Abstract:
Ageing results in increased role of vessels and lower role of myocardium in self-regulation of circulation; longer length of shift work leads to higher systolic, pulse and average dynamic BP: longer length of dispatching work causes higher ratio of systolic BP to pulse rate. Shift work increases occurrence of unfavorable cardiovascular changes by 4-12 years; peculiarities of the dispatcher's work speed this course by extra 2 years. The earliest unfavorable changes with the process are seen in vascular portion.
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