[Clinical and pathogenetic features of bronchial asthma in patients with concomitant Bauhin's valve failure]

Combination of bronchial asthma (BA) with Bauhin's valve failure (BVF) is characterized by exogenic form of BA, extrapulmonary allergy, digestion problems. Examination of 36 such patients using endoscopy, manometry and tube duodenography has shown frequent chronic disorder of duodenal patency and gastroesophageal reflux, dysbacteriosis of the large and small intestines. High concentration of middle mass molecular peptides reflects endogenic intoxication associated with abnormal composition of intestinal microflora. The above alterations give grounds to consider BVF as a factor of BA pathogenesis.