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Conducting pharmacoepidemiologic research in Denmark.

J Hallas1

  • 1Department of Clinical Pharmacology, University of Southern Denmark, Odense, Winsløwsparken 19,3, DK-5000 Odense, Denmark. j.hallas@dadlnet.dk

Pharmacoepidemiology and Drug Safety
|May 1, 2002
PubMed
Summary

Denmark offers extensive, high-quality health registries ideal for research. Linking these datasets is feasible, though challenges like cost and ethical guidelines remain for observational studies.

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Area of Science:

  • Public Health
  • Health Informatics
  • Epidemiology

Background:

  • Denmark possesses comprehensive, high-quality, population-based registries for medical and social services.
  • These registries utilize a unique person identifier, enabling data linkage.
  • Two key prescription registries, OPED and NJPD, each cover 0.5 million individuals.

Purpose of the Study:

  • To describe the characteristics and research potential of Danish health and social service registries.
  • To highlight the feasibility of record-linkage studies in Denmark.
  • To identify current obstacles to conducting such research.

Main Methods:

  • Description of the Danish healthcare and social service registration system.
  • Overview of the Open Prescription Database (OPED) and the National Patient Registry (NJPD).

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  • Discussion of the implications of the Danish data protection act on registry research.

    • Main Results:

    • Danish registries are population-based with high data quality and mutual person identifiers.
    • The OPED and NJPD are valuable resources, each covering 500,000 individuals.
    • The recent data protection act represents a liberalization of registry practices.

    Conclusions:

    • Denmark's registry infrastructure is highly suitable for record-linkage research.
    • Key challenges for record-linkage studies include funding, academic resources, and ethical guidelines for observational research.
    • Despite obstacles, the potential for robust epidemiological research using Danish registries is significant.