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Endophthalmitis caused by Moraxella osloensis.
Audina M Berrocal1, Ingrid U Scott, Darlene Miller
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, PO Box 016880, Miami, FL 33101, USA.
Summary
This study reports the first cases of endophthalmitis caused by Moraxella osloensis, a rare bacterial infection. Prompt treatment with antibiotics and surgery led to favorable visual outcomes in affected patients.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Endophthalmitis is a serious intraocular infection that can lead to vision loss.
- Delayed-onset, bleb-associated endophthalmitis often has a poorer prognosis.
Observation:
- Moraxella osloensis was identified as the causative agent in three cases of endophthalmitis.
- All cases presented as delayed-onset and were associated with glaucoma drainage devices (bleb-associated).
- The bacterium was isolated using standard microbiological techniques and automated identification systems.
Findings:
- Moraxella osloensis demonstrated sensitivity to common antibiotics like ceftazidime, ciprofloxacin, and aminoglycosides.
- Despite poor initial vision, patients achieved baseline vision recovery after treatment.
- Treatment involved pars plana vitrectomy and intravitreal antibiotic injections.
Implications:
- This is the first reported instance of endophthalmitis specifically caused by Moraxella osloensis.
- The findings suggest a generally favorable visual prognosis for Moraxella osloensis endophthalmitis, contrasting with other bleb-associated infections.
- Highlights the importance of identifying causative pathogens for targeted treatment of endophthalmitis.