Esophageal melanotic schwannoma presenting with superior vena caval obstruction

A rare tumor with an unusual presentation can pose a diagnostic and management dilemma. In this paper, we will discuss the management of a 47-year-old lady with melanotic schwanoma of the esophagus who presented with superior vena caval obstruction. The initial histological diagnosis of esophageal metastatic malignant melanoma did not corroborate the clinical and operative findings. Further evaluation revealed positivity for HMB45, S-100 protein, and vimentin, and confirmed the diagnosis of melanotic schwannoma.