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Inclusion complex of conjugated linoleic acid (CLA) with cyclodextrins
Cherl W Park1, Seck J Kim, Sook J Park
1Division of Applied Life Sciences and Institute of Agriculture and Life Sciences, Graduate School, Gyeongsang National University, Chinju 660-701, Korea.
Abstract:
Conjugated linoleic acid (CLA) inclusion complexes with alpha-cyclodextrin (alpha-CD), beta-cyclodextrin (beta-CD), and gamma-cyclodextrin (gamma-CD) (designated CLA/CDs inclusion complexes) were prepared to determine the mole ratio of CLA complexed with CDs and the oxidative stability of CLA in the CLA/CDs inclusion complexes. When measured by GC, (1)H NMR, and T(1) value analyses, 1 mole of CLA was complexed with 5 mol of alpha-CD, 4 mol of beta-CD, and 2 mol of gamma-CD. The oxidation of CLA induced at 35 degrees C for 80 h was completely prevented by the formation of CLA/CDs inclusion complexes.