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Clinical, electrophysiological, and serological overlap between Miller Fisher syndrome and acute sensory ataxic
H Shimamura1, H Miura, Y Iwaki
1Fifth Department of Internal Medicine, Tokyo Medical University, Ibaraki, Japan.
Abstract:
We report a patient with severe sensory ataxia, areflexia, and ophthalmoplegia with preservation of limb muscle strength. Electrophysiological examinations revealed peripheral sensory nerve involvement. A serological examination showed the elevation of IgG antibodies to various b-series gangliosides as well as GT1a. These indicated that this case is an overlap between acute sensory ataxic neuropathy and Miller Fisher syndrome. Autoantibody is implicated as potential pathogenic agents in some cases of acute sensory ataxic neuropathy.
