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Related Experiment Videos

Idiopathic external root resorption associated to hypercalciuria.

M C Llena-Puy1, J Amengual-Lorenzo, L Forner-Navarro

  • 1Unidad Docente de Patologia y Terap utica Dental, Departamento de Estomatologia, Universidad de Valencia, Spain. llena@uv.es

Medicina Oral : Organo Oficial De La Sociedad Espanola De Medicina Oral Y De La Academia Iberoamericana De Patologia Y Medicina Bucal
|May 2, 2002
PubMed
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Idiopathic external root resorption (IERR) in permanent teeth is rare. This study links IERR to mild calciuria and kidney stones in three patients, suggesting a potential connection requiring further investigation.

Area of Science:

  • Dentistry
  • Nephrology
  • Genetics

Background:

  • External root resorption (ERR) is common in primary teeth but rare in permanent teeth.
  • Idiopathic external root resorption (IERR) lacks a clear cause in most cases.
  • Hypercalciuria, often idiopathic, can be linked to nephrolithiasis and genetic factors.

Observation:

  • Three cases of IERR in permanent dentition were observed.
  • These cases presented with mild calciuria and a history of nephrolithiasis.
  • Patients exhibited normal blood calcium levels despite hypercalciuria.

Findings:

  • The study highlights the unusual coexistence of IERR, normocalcemic hypercalciuria, and nephrolithiasis.
  • This combination suggests a potential underlying systemic link.

Related Experiment Videos

  • The CLCN5 gene mutation, associated with some hypercalciuria and nephrolithiasis, was not uniformly present.

    • Implications:

    • Further research is needed to explore the association between IERR, hypercalciuria, and nephrolithiasis.
    • This finding may prompt a re-evaluation of diagnostic approaches for IERR.
    • Understanding this association could lead to novel diagnostic or therapeutic strategies.