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Updated: Oct 1, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
Published on: April 1, 2019
[A short tandem repeat polymorphism in the inducible nitric oxide synthase gene in Chinese population]
Xing Lü1, Ping Lu, Rui-Yun Xing
1Department of Biochemistry & Molecular Biology, Institute of Radiation Medicine, Beijing 100850, China. lvx@nic.bmi.ac.cn
Abstract:
Polymorphism of the (CCTTT)n repeat, a short tandem repeats (STR) located in promoter region of the inducible nitric oxide synthase (iNOS) gene, was analyzed in a total of 316 Chinese healthy subjects. Twelve alleles and forty-nine genotypes were identified. Three alleles that had not been reported previously, namely 17-repeats, 18-repeats and 19-repeats, were found in Chinese population. Mendelian inheritance of the allele in a family composed of three generations was determined. Some of the observed allele frequency of this STR locus in Chinese differed significantly from that of Caucasians in England.
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