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Splenectomy in a case of splenic vein thrombosis unmasks essential thrombocythemia

R Das1, U Kaur, G Garewal

  • 1Department of Haematology, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India.

Clinical and Laboratory Haematology
|May 3, 2002
PubMed

We report a patient with splenic vein thrombosis (SVT) in whom splenectomy resulted in the unmasking of essential thrombocythemia (ET). He had portal hypertension with haematemesis, resulting in anaemia requiring repeated blood transfusions. Investigations revealed SVT. Following splenectomy, he suffered a transient ischaemic attack episode, associated with persistent thrombocytosis (> 2000 x 10(9)/l). Other myeloproliferative disorders were excluded and a diagnosis of ET was established. He responded to hydroxyurea but, due to financial constraints, he discontinued treatment and subsequently relapsed. The association of ET with SVT is rare and the diagnosis of ET was missed initially as the platelet count was normal prior to splenectomy.

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