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Ischaemic nephropathy: can we preserve renal function?

D G Vidt1

  • 1Department of Nephrology/Hypertension, Cleveland Clinic Foundation and Professor of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.

Journal of Human Hypertension
|May 3, 2002
PubMed
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Renal artery stenosis, a cause of kidney failure, can often be treated. Non-invasive tests help identify correctable renovascular disease, guiding therapy decisions for hypertension and kidney dysfunction.

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • Atherosclerotic renal artery stenosis is a common cause of progressive kidney failure.
  • Ischaemic nephropathy can often be treated effectively.
  • Advances in non-invasive diagnostics aid in identifying correctable renovascular disease.

Purpose of the Study:

  • To review the diagnostic and therapeutic approaches for atherosclerotic renal artery stenosis.
  • To highlight the importance of risk-benefit assessment before intervention.
  • To guide the selection of patients for revascularization.

Main Methods:

  • Review of current non-invasive diagnostic modalities (e.g., Doppler ultrasound, CT angiography, MR angiography).
  • Analysis of clinical outcomes following revascularization procedures.

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  • Evaluation of criteria for intervention in renovascular disease.

    • Main Results:

    • Non-invasive studies can accurately identify patients with potentially correctable renovascular disease.
    • Revascularization is primarily indicated for refractory hypertension or progressive renal dysfunction.
    • Careful pre-intervention assessment of risks versus benefits is crucial.

    Conclusions:

    • Atherosclerotic renal artery stenosis is a significant contributor to renal failure.
    • Non-invasive diagnostics improve the identification of treatable renovascular conditions.
    • Intervention decisions for renal artery stenosis require careful consideration of individual patient factors and potential outcomes.