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Fas-ligand--iron fist or Achilles' heel?
Andreas M Hohlbaum1, Rebecca R Saff, Ann Marshak-Rothstein
1Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
Clinical Immunology (Orlando, Fla.)
|May 4, 2002
Abstract:
Experimental and physiological expression of the pro-apoptotic molecule Fas-ligand can induce inflammation under certain conditions. Discussed here are the experimental situations, possible mechanisms, and pathways that mediate this response.