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Related Experiment Video

Updated: Jun 10, 2026

Rare Event Detection Using Error-corrected DNA and RNA Sequencing
10:36

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

Ordering of quantum dots using genetically engineered viruses.

Seung-Wuk Lee1, Chuanbin Mao, Christine E Flynn

  • 1Department of Chemistry and Biochemistry, Center for Nano- and Molecular Science and Technology, Texas Materials Institute, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712, USA.

Science (New York, N.Y.)
|May 4, 2002
PubMed
Summary
This summary is machine-generated.

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Researchers created a novel composite material using engineered M13 bacteriophage and zinc sulfide nanocrystals. This self-assembled hybrid film exhibits nanoscale and microscale order, demonstrating potential for advanced nanomaterials.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biotechnology

Background:

  • Genetically engineered M13 bacteriophage can self-assemble into ordered structures.
  • Zinc sulfide (ZnS) nanocrystals are versatile nanomaterials with tunable properties.
  • Controlling the interface between biological and inorganic components is crucial for advanced composite fabrication.

Purpose of the Study:

  • To fabricate a highly ordered composite material using M13 bacteriophage and ZnS nanocrystals.
  • To investigate the self-ordering capabilities of genetically engineered bacteriophage in composite formation.
  • To explore the liquid crystalline phase behavior of the hybrid material.

Main Methods:

  • Utilized a liquid crystal system for composite fabrication.

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  • Employed genetically engineered M13 bacteriophage with specific recognition moieties for ZnS.
  • Coupled bacteriophage with ZnS solution precursors to form hybrid films.
  • Controlled lyotropic liquid crystalline phase behavior using solvent concentration and magnetic fields.

    • Main Results:

    • Successfully fabricated a self-supporting hybrid film material with nanoscale and microscale order.
    • Achieved ordered domains of approximately 72-micrometers, continuous over centimeter length scales.
    • Demonstrated control over the liquid crystalline phase behavior of the hybrid material.

    Conclusions:

    • Genetically engineered M13 bacteriophage can serve as a basis for self-ordering in composite material fabrication.
    • The resulting hybrid material exhibits significant nanoscale and microscale structural organization.
    • The hybrid material's liquid crystalline properties can be tuned by external stimuli, offering potential for advanced applications.