Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitamin D and muscle function.

M Pfeifer1, B Begerow, H W Minne

  • 1Institute of Clinical Osteology Gustav Pommer and Clinic Der Füirstenhof, Bad Pyrmont, Germany. iko_pyrmont@t-online.de

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|May 7, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Whole-genome sequencing reveals two prolonged simultaneous outbreaks involving Pseudomonas aeruginosa high-risk strains ST111 and ST235 with resistance to quaternary ammonium compounds.

The Journal of hospital infection·2024
Same author

[German S1 Guideline Long-/Post-COVID].

Pneumologie (Stuttgart, Germany)·2022
Same author

COVID-19 Lockdown Periods in 2020: Good Maintenance of Metabolic Control in Adults with Type 1 and Type 2 Diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association·2022
Same author

[Statement of the German Society for Pulmonology and Respiratory Medicine Regarding the Regulation to Use FFP and Surgical Masks in the General Population].

Pneumologie (Stuttgart, Germany)·2021
Same author

[S2k Guideline - Recommendations for Inpatient Therapy of Patients with COVID-19].

Pneumologie (Stuttgart, Germany)·2021
Same author

[Weaning in a Pandemic Situation - A Position Paper].

Pneumologie (Stuttgart, Germany)·2020
Same journal

Chronic kidney disease and sarcopenia.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same journal

Denosumab therapy is associated with a reduced risk of clinically diagnosed rotator cuff tears: a multi-institutional real-world cohort study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same journal

Clarifying the romosozumab "Super-Responder" phenotype: response to methodological concerns.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same journal

Correction to: Melatonin at pharmacological concentrations suppresses osteoclastogenesis via the attenuation of intracellular ROS.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same journal

Letter to the Editor: multiplicity, microbiome interventions, and measurement biases in bone health biomarkers.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
Same journal

Association between myosteatosis and bone mineral density in postmenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
See all related articles

Vitamin D plays a crucial role in muscle function through genomic and non-genomic pathways. Maintaining adequate vitamin D levels is essential for preventing muscle weakness and improving neuromuscular function, especially in the elderly.

Area of Science:

  • Endocrinology
  • Muscle Physiology
  • Nutritional Science

Background:

  • Vitamin D influences muscle tissue via genomic and non-genomic mechanisms.
  • Vitamin D receptor (VDR) gene polymorphisms may impact muscle function.
  • Vitamin D production is affected by factors like age, latitude, and skin pigmentation.

Purpose of the Study:

  • To review current knowledge on the relationship between vitamin D and muscle function.
  • To explore the molecular mechanisms underlying vitamin D's effects on muscle.
  • To discuss the clinical implications of vitamin D deficiency on muscle health.

Main Methods:

  • Literature review of studies on vitamin D and muscle.
  • Analysis of molecular mechanisms (genomic and non-genomic effects).

Related Experiment Videos

  • Examination of clinical data linking vitamin D levels to muscle strength and gait.

    • Main Results:

    • Low serum 25-hydroxyvitamin D levels (<50 nmol/l) correlate with increased body sway and decreased muscle strength (<30 nmol/l).
    • Osteomalacic myopathy presents with gait disturbances, difficulty rising, and muscle pain.
    • Vitamin D and calcium supplementation may enhance neuromuscular function in deficient elderly individuals.

    Conclusions:

    • Vitamin D deficiency is common, particularly in the elderly and those in northern latitudes.
    • Maintaining sufficient vitamin D levels is vital for preserving muscle strength and function.
    • Supplementation with vitamin D and calcium can mitigate risks of fractures and improve neuromuscular outcomes.