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Use of transgenic models to understand effects of exercise on glucose metabolism

Bo F Hansen1, Jørgen F P Wojtaszewski

  • 1Department of Diabetes Biology, Novo Nordisk, Bagsvaerd, Denmark.

Exercise and Sport Sciences Reviews
|May 7, 2002
PubMed

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Glucose Homeostasis: Regulation of Blood Glucose01:02

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Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...