[Aminopeptidases in the serum following myocardial infarct]

In 19 patients wiht myocardial infarction during 7 weeks after the onset of the infarction the serum activities of the leucine aminopeptidase (LAP) and of the alanine aminopeptidase (AAP) were determined. Here an increase of the LAP-values with a maximum in the 1st week was found. Apparantly a hypoxic lesion of the hepatocytes is to be regarded as cause for this. In patients with shock symptomatology as well as with heart decompensation the AAP-activities were on the average higher than in the cases with myocardial infarction without these alterations during the whole period of observation. In all myocardial infarctions the AAP-zymograms showed an additional anodic AAP-fraction as it was observed in previous investigations in cholestasis.