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Gorham disease of the orbit
Gregory B Krohel1, Kenn Freedman, George B Peters
1Department of Ophthalmology, Albany Medical College, Albany, New York, USA.
American Journal of Ophthalmology
|May 7, 2002
Summary
Gorham disease, or vanishing bone disease, can affect the orbit, causing lytic bone lesions. Surgical intervention improved symptoms in a patient with this rare condition.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Gorham disease (GD), also known as vanishing bone disease, is a rare idiopathic disorder characterized by progressive osteolysis.
- Orbital involvement is uncommon, making diagnosis challenging.
Observation:
- A 43-year-old woman presented with temple depression, eyelid pulsatile sensation, proptosis, and headache.
- Imaging revealed a lytic lesion in the left orbital roof.
Findings:
- Intraoperative findings confirmed a bony defect in the orbital roof.
- Pathological examination excluded malignancy and other neoplastic processes.
- Surgical intervention led to symptomatic improvement.
Implications:
- Gorham disease should be included in the differential diagnosis for patients with unexplained lytic orbital bone lesions.
- Early recognition and appropriate management are crucial for favorable outcomes in orbital Gorham disease.