Carcinoma of duodenum arising from Brunner's gland
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Updated: Oct 1, 2026

Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors
Published on: December 20, 2024
Kimishige Akino1, Yoshihiro Kondo, Atsumori Ueno
1Department of Gastroenterology, Muroran General Hospital, Japan.
Abstract:
Primary carcinoma of the duodenum is a rare lesion. In conjunction with the widespread use of panendoscopy, reported cases of carcinoma of the duodenum have recently increased. Although benign hyperplasia of Brunner's gland is well documented, duodenal carcinoma originating in Brunner's gland is extremely rare, and, consequently, there is little data on the morphological or histochemical characteristics. We report here a case of early duodenal carcinoma arising from Brunner's gland, whose origin was proven by mucin immunohistochemistry.
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