Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

What is the 'true' function of skin?

C M Chuong1, B J Nickoloff, P M Elias

  • 1Department of Pathology, University of Southern California, Los Angeles, 90033, USA. chuong@pathfinder.hsc.usc.edu

Experimental Dermatology
|May 8, 2002
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of the atrophogenicity of corticosteroids to human skin using non-invasive methods.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016
Same author

The future of bioengineering A dermatologist's perspective.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016
Same author

Mechanisms of eccrine anidrosis. I. High level blockade.

The Journal of investigative dermatology·2015
Same author

The SLS provocative patch test in allergic contact sensitization.

The Journal of investigative dermatology·2015
Same author

Corneobiology and corneotherapy--a final chapter.

International journal of cosmetic science·2011
Same author

A new species of Cephalosporium in Madura foot (Cephalosporium granulomatis).

Journal of bacteriology·2010

The skin is more than a barrier; it

Area of Science:

  • Cutaneous Biology
  • Dermatology
  • Immunology
  • Endocrinology
  • Neuroscience

Background:

  • Conventional views of skin focus on its barrier and sensory functions.
  • Emerging research reveals the skin as a complex biofactory and integral part of immune, nervous, and endocrine systems.
  • These newly appreciated skin functions are crucial for understanding and treating dermatological conditions.

Purpose of the Study:

  • To present a comprehensive overview of the skin's multifaceted functions beyond its classical roles.
  • To highlight the skin's emerging functions as a biofactory and its integration with other major body systems.
  • To stimulate new therapeutic strategies by exploring these advanced cutaneous functions.

Main Methods:

Related Experiment Videos

  • Review of current scientific literature and expert opinions.
  • Discussion of emerging research on skin's biofactory capabilities and systemic interactions.
  • Exploration of evolutionary and embryological origins of skin functions.

Main Results:

  • The skin actively synthesizes, processes, and metabolizes a wide array of molecules.
  • Intracutaneous communication pathways link the skin with the immune, nervous, and endocrine systems.
  • These complex functions offer novel therapeutic targets for dermatological interventions.

Conclusions:

  • The skin possesses extensive functions beyond barrier and sensory roles, including significant metabolic and signaling activities.
  • Understanding the skin's integration with the immune, nervous, and endocrine systems is vital for clinical dermatology.
  • Future research should focus on harnessing these comprehensive skin functions for advanced therapeutic applications.