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Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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v-Src's hold over actin and cell adhesions

Margaret C Frame1, Valerie J Fincham, Neil O Carragher

  • 1The Beatson Institute for Cancer Research, Cancer Research UK Beatson Laboratories, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK. mframe@beatson..gla.ac.uk

Nature Reviews. Molecular Cell Biology
|May 8, 2002
PubMed
Summary

The oncogenic protein v-Src and its cellular form, c-Src, are tyrosine kinases. These kinases regulate cell adhesion and actin cytoskeleton dynamics, impacting cell behavior and potentially driving cancer progression.

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