Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thromboembolic problems after the Fontan operation.

Paul Monagle1, Tom R Karl

  • 1Division of Laboratory Services, Royal Children's Hospital, Parkville, Victoria, Australia.

Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
|May 8, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Secondary Anticoagulation Prophylaxis for Children with Antiphospholipid Syndrome: A Systematic Review and Meta-Analysis.

Blood advances·2026
Same author

Transfusion of blood products to neonatal and pediatric extracorporeal membrane oxygenation patients: A prospective, observational study.

Transfusion·2026
Same author

Outcomes After Single-Stage Fontan Palliation: A Propensity Score-Matched Analysis from the Australia-New Zealand Fontan Registry.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Treatment and outcomes of thromboembolism in paediatric patients with cardiac disease in a cardiac ICU: a single-centre retrospective study.

Cardiology in the young·2026
Same author

Reference intervals for haptoglobin in neonates and children 30 days to 18 years old.

Scandinavian journal of clinical and laboratory investigation·2026
Same author

Aortic valvar atresia with ventricular septal defect with well-developed mitral valve and balanced ventricles may mimic common arterial trunk.

Cardiology in the young·2026
Same journal

Surgical Approaches for Vascular-Related Aerodigestive Compression.

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
Same journal

Transcatheter Interventional Options in Pulmonary Vein Stenosis: When to Stent?

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
Same journal

Airway Malacia: Stent Innovations and Emerging Ex Vivo Testing Platforms.

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
Same journal

Bilateral Bronchus Suis Tracheoplasty.

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
Same journal

Pulmonary Atresia With Major Aorto-Pulmonary Collateral Arteries (MAPCAs): Timing and Type of Intervention.

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
Same journal

Pulmonary Atresia With Intact Ventricular Septum: Expert Review of the Surgical Management.

Seminars in thoracic and cardiovascular surgery. Pediatric cardiac surgery annual·2026
See all related articles

Thromboembolic events (TE) are a significant risk after Fontan surgery. Current evidence is insufficient to recommend optimal prophylaxis, highlighting the need for further research.

Area of Science:

  • Cardiology
  • Pediatric Surgery
  • Hematology

Background:

  • Thromboembolic events (TE) are a major cause of morbidity and mortality following the Fontan operation.
  • The Fontan procedure is a palliative surgery for complex congenital heart disease, creating a single ventricle physiology.

Purpose of the Study:

  • To comprehensively assess the current knowledge regarding TE after Fontan surgery.
  • To analyze the incidence, risk factors, and prophylactic strategies for TE in Fontan patients.

Main Methods:

  • A comprehensive MEDLINE literature search was conducted from 1971 to 2000.
  • Fifty-one relevant studies were identified and analyzed, including case reports, retrospective cohort studies, and cross-sectional surveys.

Main Results:

Related Experiment Videos

  • Analysis of 51 studies revealed insufficient evidence to establish clear recommendations for optimal anticoagulant prophylaxis.
  • The literature review identified a need to further investigate the incidence, morbidity, mortality, and risk factors associated with TE post-Fontan surgery.

Conclusions:

  • There is currently insufficient evidence to guide optimal prophylactic strategies against thromboembolic events after Fontan surgery.
  • Multicenter randomized controlled trials comparing antiplatelet and anticoagulation therapies are essential for developing evidence-based guidelines.