Related Experiment Video
Updated: Aug 22, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
Use of cholesterol-lowering therapy by elderly adults after myocardial infarction
John Z Ayanian1, Mary Beth Landrum, Barbara J McNeil
1Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA. ayanian@hcp.med.harvard.edu
Background:
Use of cholesterol-lowering drugs reduces mortality and adverse cardiac events among people aged 65 to 75 years with coronary heart disease, but previous studies have shown that most patients have not received this treatment.
Methods:
We conducted a telephone survey during 1999 and 2000 of 815 Medicare beneficiaries aged 65 to 74 years hospitalized for an acute myocardial infarction in California, Florida, Massachusetts, New York, or Pennsylvania during 1994 and 1995. Outcome measures included use of cholesterol-lowering drugs, beliefs about the importance of lowering cholesterol levels, and knowledge of personal cholesterol levels, adjusting for demographic and clinical factors using logistic regression.
Results:
Among respondents, 59.4% reported taking a cholesterol-lowering drug, but most were not aware of potential adverse effects. In adjusted analyses, drug treatment was significantly more common among women, patients aged 65 to 69 years, and those who reported that a cardiologist was mainly responsible for their cholesterol management. Lowering cholesterol levels was viewed as "very important" by 77.2% of respondents, but significantly less often by men, older patients, and those with diabetes mellitus or congestive heart failure. Only 33.1% of respondents knew their cholesterol level, and this knowledge was significantly less common among black patients and those with diabetes mellitus or congestive heart failure.
Conclusions:
Use of cholesterol-lowering drugs was much greater than in previous studies of elderly patients after myocardial infarction, demonstrating increased attention to secondary prevention. However, most patients were unaware of their cholesterol level or potential adverse effects of drug treatment, indicating that they may benefit from greater education about cholesterol testing and treatment.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Coronary Artery Disease IV: Preventive Measures
Coronary Artery Disease V: Interprofessional Care
Angina IV: Management
Atherosclerosis III: Management
Atherosclerosis IV: Nursing Management
