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3-Deoxy-1beta,20-dihydroxyecdysone from the leaves of Diploclisia glaucescens
Lalith Jayasinghe1, Champika P Jayasooriya, Kiyoshi Oyama
1Institute of Fundamental Studies, Hantana Road, Kandy, Sri Lanka. lalith@ifs.ac.lk
Abstract:
Chemical investigation of methanol extract of the leaves of Diploclisia glaucescens of the family Menispermaceae furnished a new ecdysteroid, 3-deoxy-1beta,20-dihydroxyecdysone. The structure of the new ecdysteroid was established on detailed analysis of spectral data. The 3-deoxy ecdysteroid showed 40% potency of 20-hydroxyecdysone in the spiracle index assay using the fourth instar larvae of the silkworm Bombyx mori.
