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Updated: Jul 28, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
Histopathologic ocular examination after lensectomy in a Macacus rhesus monkey, an unexpected event of secondary
F D Koole1, G L van der Heijde
1Department of Ophthalmology, Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands. FD.Koole@vumc.nl
Abstract:
In a Macacus rhesus monkey an unilateral lensectomy was performed on the 15th day of life to study the emmetropization proces. During a period of 20.5 months refractional state, axial length, corneal dioptric power and intraocular pressure were measured in the aphakic and fellow eye. Results showed that axial elongation of the aphakic eye was larger in comparison to the phakic fellow eye. Histopathologic examination of the aphakic eye revealed glaucomatous changes due to obstruction in the anterior chamber angle.

