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Successful planned pregnancy in a patient with St Jude medical prosthetic mitral valve

Tsuyoshi Fukuda1, Tatsuo Yokoyama, Masaki Otaki

  • 1Division of Pediatric Cardiology, Kinki University School of Medicine, Osaka, Japan. fukuda@kpcd.med.kindai.ac.jp

Circulation Journal : Official Journal of the Japanese Circulation Society
|May 10, 2002
PubMed

A primiparous woman with a St Jude Medical (SJM) mitral valve prosthesis and receiving anticoagulant drug delivered a healthy male infant by spontaneous normal vaginal delivery. Oral warfarin was replaced by subcutaneous heparin at the 6th week of gestation and the dosage of heparin was adjusted to maintain a partial thromboplastin time between 2.0 and 2.5 times the control value. Treatment with heparin was administered during the first trimester and the last 5 weeks of gestation. Warfarin was used between the 13th and 32nd week. Successful pregnancy and delivery in patients with a SJM mitral valve prostheses is possible with careful maintenance of anticoagulation.

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