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The Ask-Upmark kidney. Roentgenographic and pathological features.
American Journal of Diseases of Children (1960)
|December 1, 1975
Summary
Ask-Upmark kidney is a rare form of kidney hypoplasia often linked to hypertension. Early recognition is crucial for potentially curable cases, especially when localized to one kidney.
Area of Science:
- Nephrology
- Vascular Medicine
- Pediatric Nephrology
Background:
- Segmental renal hypoplasia is a rare congenital anomaly affecting kidney development.
- The Ask-Upmark kidney is a specific, often localized, form of this condition.
- Hypertension is a common and significant comorbidity associated with this entity.
Observation:
- The Ask-Upmark kidney lesion can be focal or diffuse.
- It may affect one or both kidneys.
- Association with hypertension is nearly universal.
Findings:
- This condition presents as a distinct pattern of renal hypoplasia.
- The presence of hypertension underscores the vascular component of the disease.
- Distinguishing Ask-Upmark kidney from other causes of hypertension is critical.
Implications:
- Early diagnosis of Ask-Upmark kidney is essential for effective management.
- Localized forms offer a potential for curative treatment of hypertension.
- Recognition prevents misdiagnosis and ensures appropriate therapeutic strategies for renovascular hypertension.