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Related Experiment Videos

The Ask-Upmark kidney. Roentgenographic and pathological features.

E Himmelfarb, J G Rabinowitz, L Parvey

    American Journal of Diseases of Children (1960)
    |December 1, 1975
    PubMed
    Summary

    Ask-Upmark kidney is a rare form of kidney hypoplasia often linked to hypertension. Early recognition is crucial for potentially curable cases, especially when localized to one kidney.

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    Area of Science:

    • Nephrology
    • Vascular Medicine
    • Pediatric Nephrology

    Background:

    • Segmental renal hypoplasia is a rare congenital anomaly affecting kidney development.
    • The Ask-Upmark kidney is a specific, often localized, form of this condition.
    • Hypertension is a common and significant comorbidity associated with this entity.

    Observation:

    • The Ask-Upmark kidney lesion can be focal or diffuse.
    • It may affect one or both kidneys.
    • Association with hypertension is nearly universal.

    Findings:

    • This condition presents as a distinct pattern of renal hypoplasia.
    • The presence of hypertension underscores the vascular component of the disease.
    • Distinguishing Ask-Upmark kidney from other causes of hypertension is critical.

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    Implications:

    • Early diagnosis of Ask-Upmark kidney is essential for effective management.
    • Localized forms offer a potential for curative treatment of hypertension.
    • Recognition prevents misdiagnosis and ensures appropriate therapeutic strategies for renovascular hypertension.