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Resveratrol and cancer: a review

J F Savouret1, M Quesne

  • 1INSERM unité 135, Hopital de Bicêtre CHU level 3, Le Kremlin-Bicêtre, France. savouret@kb.inserm.fr

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|May 10, 2002
PubMed

Insights

Resveratrol, a stilbene phytoalexin, offers promising research directions for cancer prevention and treatment. Its properties are particularly relevant for understanding and combating xenobiotic-induced carcinogenesis.

Area of Science:

  • Phytochemistry
  • Molecular Biology
  • Cancer Research

Background:

  • Resveratrol is a naturally occurring stilbene phytoalexin found in various plants.
  • Phytoalexins are compounds produced by plants to protect against pathogens.
  • Resveratrol has demonstrated diverse biological activities, including antioxidant and anti-inflammatory effects.

Purpose of the Study:

  • To explore the chemopreventive and chemotherapeutic potential of Resveratrol.
  • To investigate the role of Resveratrol in the context of xenobiotic-related carcinogenesis.
  • To highlight Resveratrol as a subject for novel research avenues.

Main Methods:

  • Literature review of Resveratrol's properties and biological activities.
  • Analysis of studies focusing on Resveratrol's effects on carcinogenesis.
  • Examination of Resveratrol's interaction with xenobiotic metabolism and pathways.

Main Results:

  • Resveratrol exhibits multifaceted properties applicable to cancer chemoprevention and chemotherapy.
  • Evidence suggests Resveratrol's potential in mitigating risks associated with xenobiotic-induced cancers.
  • The compound's mechanisms of action warrant further in-depth investigation.

Conclusions:

  • Resveratrol presents significant opportunities for developing new strategies in cancer prevention and treatment.
  • Further research into Resveratrol's role in xenobiotic carcinogenesis is crucial.
  • The therapeutic potential of Resveratrol in oncology is a promising area for scientific exploration.

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