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Facile and regioselective synthesis of phenylpropanoid-substituted flavan-3-ols
Suresh Awale1, Yasuhiro Tezuka, Shumin Wang
1Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630-Sugitani, 930-0194, Japan.
Organic Letters
|May 10, 2002
Abstract:
[reaction: see text] A highly efficient, facile, one-pot regioselective synthesis of a series of phenylpropanoid-substituted flavan-3-ols is described. The mechanism involves dienone-phenol rearrangement followed by a Michael-type reaction.