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Updated: Oct 1, 2026
Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy
Published on: November 29, 2018
Granulomatous lesions of the homolateral limb after previous mastectomy
A Virgili1, C Maranini, A Califano
1Department of Clinical and Experimental Medicine, Section of Dermatology, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy. vri@unife.it
Background:
Granulomas may be classified as palisaded, sarcoidal, tuberculoid, suppurative and foreign body. In cancer patients they are defined as tumour-related sarcoid granulomas. Otherwise they are classified as granulomatous lesions of unknown significance. It is still unknown why neoplastic diseases are sometimes associated with granulomas.
Objectives:
To investigate granulomas found on the same side as a previous mastectomy.
Methods:
We studied four women who had previously undergone mastectomy and presented with epithelioid cell granulomas of the same side as the previous mastectomy.
Conclusions:
The association between breast cancer and host granulomatous reaction is uncommon. The cases discussed may correspond to cutaneous tumour-related sarcoid granuloma reactions.
