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Case report. Nattrassia mangiferae endophthalmitis
Tawanda Gumbo1, Ndodini Mkanganwi, Valerie J Robertson
1Department of Medicine, University of Zimbabwe Medical School, Harare, Zimbabwe.
Mycoses
|May 10, 2002
Summary
Nattrassia mangiferae, a plant pathogen, rarely causes invasive human infections. This case highlights its potential role in eye infections following plant trauma, with ketoconazole showing treatment promise.
Area of Science:
- Mycology
- Ophthalmology
- Infectious Diseases
Background:
- Nattrassia mangiferae is a fungus known to infect plants and occasionally cause human skin infections.
- Invasive human infections by N. mangiferae are exceptionally rare in medical literature.
Observation:
- A 60-year-old immunocompetent patient developed endophthalmitis after ocular injury from grass.
- Microbiological analysis of aqueous humor identified Nattrassia mangiferae.
Findings:
- The patient's endophthalmitis resolved following treatment with oral ketoconazole.
- This case demonstrates N. mangiferae as a potential cause of invasive infection after plant penetration injuries.
Implications:
- Nattrassia mangiferae should be considered in cases of endophthalmitis following eye trauma, particularly in agricultural or outdoor settings.
- Ketoconazole represents a viable therapeutic option for N. mangiferae infections, especially in resource-limited regions.