[Synovial diseases of the hip]
Related Experiment Video
Updated: Oct 1, 2026

A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture
Published on: March 20, 2026
Xavier Le Loët1, Sophie Pouplin, Olivier Vittecoq
1Service de rhumatologie Centre hospitalier universitaire, Rouen-Hôpitaux, INSERM U519 et IFR 23, Rouen, Rouen. xavier.le-loet@chu-rouen.fr
Abstract:
Synovial diseases of the hip are often overlooked because they are far less frequent that osteoarthritis and because this joint is deep and so difficult to examine. The more important cause is septic arthritis; it requires an hospitalization in emergency. Synovial tissue may also be at the beginning of the spondylarthropathy or, more rarely, of rheumatoid arthritis. In acute forms, diagnosis must be done before any radiological destructive changes. Aspiration of the hip and synovial biopsy are necessary for the diagnosis. In subacute or chronic forms, computed tomography and/or magnetic resonance imaging are useful tools to suspect the diagnosis and to guide a biopsy.
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