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Related Experiment Videos

Arterial pulse wave reflection as feedback.

Christopher M Quick1, David S Berger, Abraham Noordergraaf

  • 1Center for Cerebrovascular Research, University of California, San Francisco 94110, USA. quickc@anesthesia.ucsf.edu

IEEE Transactions on Bio-Medical Engineering
|May 11, 2002
PubMed
Summary
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Apparent arterial compliance (C(app)) offers a new way to understand arterial system dynamics. This method, unlike input impedance (Z(in)), better interprets how pulse wave reflections affect blood storage and flow.

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Hemodynamics

Background:

  • Input impedance (Z(in)) traditionally characterizes arterial system dynamics, focusing on impedance to blood flow.
  • A new metric, apparent arterial compliance (C(app)), has been developed to describe dynamic blood storage.
  • Both Z(in) and C(app) are influenced by pulse wave propagation and reflection.

Purpose of the Study:

  • To introduce and explain apparent arterial compliance (C(app)) as a novel descriptor of arterial system dynamics.
  • To demonstrate how C(app) conceptualizes arterial system behavior, particularly concerning pulse wave reflections.
  • To illustrate how C(app) can be used to interpret changes in arterial system dynamics due to altered arterial compliance.

Main Methods:

  • Analytical formulas were used to model the arterial system.

Related Experiment Videos

  • Large-scale arterial system modeling was performed.
  • Direct analysis of experimental or simulated data was conducted.

    • Main Results:

    • Apparent arterial compliance (C(app)) provides a functional description of the arterial system, amenable to negative feedback analysis.
    • Pulse wave reflection impacts the gain and bandwidth of pulsatile volume storage.
    • The conceptualization of reflection via C(app) offers new interpretations of arterial system dynamics.

    Conclusions:

    • Apparent arterial compliance (C(app)) presents a valuable new framework for understanding arterial system dynamics, independent of cardiac properties.
    • This approach offers enhanced interpretation of how arterial compliance changes affect hemodynamics.
    • The study highlights the utility of C(app) in analyzing the effects of pulse wave reflection on blood storage and flow dynamics.